| Item Type | Name |
|
Concept
|
Antibodies, Bacterial
|
|
Concept
|
Antigens, Ly
|
|
Concept
|
Agglutination Tests
|
|
Concept
|
alpha-Fetoproteins
|
|
Concept
|
Abelson murine leukemia virus
|
|
Concept
|
Ampicillin Resistance
|
|
Concept
|
Binding Sites, Antibody
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Antigens
|
|
Concept
|
Antigens, Surface
|
|
Concept
|
Animals
|
|
Concept
|
Antibodies, Anti-Idiotypic
|
|
Concept
|
Antigens, Bacterial
|
|
Concept
|
Histocompatibility Antigens Class II
|
|
Concept
|
B-Lymphocytes
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Movement
|
|
Concept
|
Autoantigens
|
|
Concept
|
Autoantibodies
|
|
Concept
|
Binding Sites
|
|
Concept
|
Cell Separation
|
|
Concept
|
Carcinoma, Krebs 2
|
|
Concept
|
Cell Transformation, Viral
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Codon
|
|
Concept
|
Genes, Immunoglobulin
|
|
Concept
|
Coagulants
|
|
Concept
|
Guinea Pigs
|
|
Concept
|
Concanavalin A
|
|
Concept
|
Cosmids
|
|
Concept
|
Immunoglobulin M
|
|
Concept
|
Dogfish
|
|
Concept
|
Immunoglobulin Constant Regions
|
|
Concept
|
Insulin
|
|
Concept
|
Cytidine
|
|
Concept
|
Immunoglobulin A
|
|
Concept
|
Immunity, Active
|
|
Concept
|
Cockayne Syndrome
|
|
Concept
|
DNA, Superhelical
|
|
Concept
|
Fibrinogen
|
|
Concept
|
Introns
|
|
Concept
|
Ectoderm
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Microtubule-Associated Proteins
|
|
Concept
|
Genes, MHC Class II
|
|
Concept
|
Immune Sera
|
|
Concept
|
Immune Tolerance
|
|
Concept
|
Immunoglobulin Heavy Chains
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Herpesvirus 4, Human
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Immunoglobulin Idiotypes
|
|
Concept
|
Immunoglobulin gamma-Chains
|
|
Concept
|
Immunoglobulin J-Chains
|
|
Concept
|
Goats
|
|
Concept
|
Haptens
|
|
Concept
|
Macrophages
|
|
Concept
|
Isoelectric Point
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Metallothionein
|
|
Concept
|
Laboratories
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Models, Molecular
|
|
Concept
|
Mosaicism
|
|
Concept
|
Peyer's Patches
|
|
Concept
|
Mice, Inbred AKR
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Models, Genetic
|
|
Concept
|
Poly U
|
|
Concept
|
Poultry
|
|
Concept
|
Immunization, Secondary
|
|
Concept
|
Immunoglobulin Switch Region
|
|
Concept
|
Immunoglobulin Variable Region
|
|
Concept
|
Neomycin
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
|
Concept
|
Cricetinae
|
|
Concept
|
Hot Temperature
|
|
Concept
|
Hemolysin Proteins
|
|
Concept
|
Peritoneum
|
|
Concept
|
Nucleosomes
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
Microscopy, Electron
|
|
Concept
|
Phosphorus Isotopes
|
|
Concept
|
Poly A
|
|
Concept
|
Muscle Proteins
|
|
Concept
|
Myeloma Proteins
|
|
Concept
|
Plasmacytoma
|
|
Concept
|
Proinsulin
|
|
Concept
|
Thymoma
|
|
Concept
|
Plasma Cells
|
|
Concept
|
Protein Conformation
|
|
Concept
|
Immunoglobulin G
|
|
Concept
|
Immune Complex Diseases
|
|
Concept
|
Immunization, Passive
|
|
Concept
|
Immunoelectrophoresis
|
|
Concept
|
Immunoglobulin Joining Region
|
|
Concept
|
Puromycin
|
|
Concept
|
Receptors, Antigen, B-Cell
|
|
Concept
|
Receptors, Immunologic
|
|
Concept
|
Writing
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
Gene Rearrangement, B-Lymphocyte
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Leukemia, B-Cell
|
|
Concept
|
Hemocyanins
|
|
Concept
|
Sheep
|
|
Concept
|
Humans
|
|
Concept
|
Sulfur Radioisotopes
|
|
Concept
|
Immunoglobulin alpha-Chains
|
|
Concept
|
Immunoglobulin lambda-Chains
|
|
Concept
|
Immunoglobulin mu-Chains
|
|
Concept
|
United States
|
|
Concept
|
Terminator Regions, Genetic
|
|
Concept
|
Immunoglobulin Class Switching
|
|
Concept
|
Myogenic Regulatory Factors
|
|
Concept
|
Lymphoid Tissue
|
|
Concept
|
Mathematics
|
|
Concept
|
Codon, Terminator
|
|
Concept
|
Gene Rearrangement, T-Lymphocyte
|
|
Concept
|
Peanut Agglutinin
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
B-Lymphocyte Subsets
|
|
Concept
|
Mutagenesis
|
|
Concept
|
Mice, Inbred DBA
|
|
Concept
|
TATA Box
|
|
Concept
|
Lymph Nodes
|
|
Concept
|
Lymphoma
|
|
Concept
|
Microinjections
|
|
Concept
|
Microscopy
|
|
Concept
|
Microsomes
|
|
Concept
|
Multiple Myeloma
|
|
Concept
|
Gene Rearrangement, B-Lymphocyte, Heavy Chain
|
|
Concept
|
Gene Rearrangement, B-Lymphocyte, Light Chain
|
|
Concept
|
DNA Probes
|
|
Concept
|
Scientific Misconduct
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Methionine
|
|
Concept
|
Methods
|
|
Concept
|
Methylation
|
|
Concept
|
National Institutes of Health (U.S.)
|
|
Concept
|
Neoplasms, Experimental
|
|
Concept
|
Point Mutation
|
|
Concept
|
Interferon-alpha
|
|
Concept
|
Bacteriophage P1
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Sequence Deletion
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Chemokines
|
|
Concept
|
Interferon-Stimulated Gene Factor 3
|
|
Concept
|
Interferon-Stimulated Gene Factor 3, gamma Subunit
|
|
Concept
|
Models, Immunological
|
|
Concept
|
Mice, Inbred MRL lpr
|
|
Concept
|
Fas Ligand Protein
|
|
Concept
|
Base Pair Mismatch
|
|
Concept
|
Lymphocyte Count
|
|
Concept
|
CpG Islands
|
|
Concept
|
Embryonic Development
|
|
Concept
|
5' Untranslated Regions
|
|
Concept
|
Genes, bcl-2
|
|
Concept
|
Dendritic Cells, Follicular
|
|
Concept
|
TATA-Box Binding Protein
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Pseudomonas aeruginosa
|
|
Concept
|
Mice
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Multiprotein Complexes
|
|
Concept
|
Interferon Regulatory Factors
|
|
Concept
|
Rats
|
|
Concept
|
Uridine
|
|
Concept
|
Spleen
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Temperature
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Chloramphenicol O-Acetyltransferase
|
|
Concept
|
MutS Homolog 2 Protein
|
|
Concept
|
Genes, myc
|
|
Concept
|
Thymosin
|
|
Concept
|
Lymphoma, B-Cell
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Retroviridae Proteins, Oncogenic
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Zinc Fingers
|
|
Concept
|
Proliferating Cell Nuclear Antigen
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Integrases
|
|
Concept
|
Leukocyte Common Antigens
|
|
Concept
|
Receptors, Chemokine
|
|
Concept
|
Germinal Center
|
|
Concept
|
Microsatellite Repeats
|
|
Concept
|
Somatic Hypermutation, Immunoglobulin
|
|
Concept
|
Antibodies
|
|
Concept
|
Antibody Diversity
|
|
Concept
|
Binding, Competitive
|
|
Concept
|
Blood Group Antigens
|
|
Concept
|
Chickens
|
|
Concept
|
Deoxycytidine
|
|
Concept
|
DNA, Single-Stranded
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Hemagglutination Tests
|
|
Concept
|
Hemolytic Plaque Technique
|
|
Concept
|
Hypersensitivity, Delayed
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Immunoglobulin kappa-Chains
|
|
Concept
|
Immunoglobulin Light Chains
|
|
Concept
|
Immunologic Memory
|
|
Concept
|
Kidney Tubules, Collecting
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Lymphocytes
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Microscopy, Phase-Contrast
|
|
Concept
|
Models, Biological
|
|
Concept
|
Receptors, Antigen, T-Cell
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Thymus Gland
|
|
Concept
|
Translocation, Genetic
|
|
Concept
|
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
|
|
Concept
|
Immunophenotyping
|
|
Concept
|
Mutagenesis, Insertional
|
|
Concept
|
Mice, SCID
|
|
Concept
|
DNA Primers
|
|
Concept
|
5-Methylcytosine
|
|
Academic Article
|
Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.
|
|
Academic Article
|
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation.
|
|
Academic Article
|
Identification and characterization of the murine Rag1 promoter.
|
|
Academic Article
|
Progress in understanding the mechanism and consequences of somatic hypermutation.
|
|
Academic Article
|
The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes.
|
|
Academic Article
|
Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.
|
|
Academic Article
|
Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.
|
|
Academic Article
|
A novel cytidine deaminase affects antibody diversity.
|
|
Academic Article
|
A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
|
|
Academic Article
|
Immunology. Autoreactive B cells migrate into T cell territory.
|
|
Academic Article
|
Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice.
|
|
Academic Article
|
Expression of immunoglobulin and globin genes in B and T lymphocytes and other cells.
|
|
Academic Article
|
The switch region associated with immunoglobulin C mu genes is DNase I hypersensitive in T lymphocytes.
|
|
Academic Article
|
Quantitation of immunoglobulin genes by nucleic acid hybridization with RNA from myeloma and spleen microsomes.
|
|
Academic Article
|
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.
|
|
Academic Article
|
Structural alterations in J regions of mouse immunoglobulin lambda genes are associated with differential gene expression.
|
|
Academic Article
|
Rearrangement of immunoglobulin genes.
|
|
Academic Article
|
Synthesis of specific RNA molecules during immune response in the mouse spleen.
|
|
Academic Article
|
Somatic mutation of immunoglobulin light-chain variable-region genes.
|
|
Academic Article
|
The order and orientation of mouse lambda-genes explain lambda-rearrangement patterns.
|
|
Academic Article
|
Immunoglobulin messenger RNAs of T lymphocytes.
|
|
Academic Article
|
Antibody-carrying cells in the immune response 1. Identification of "rosette"-forming cells by light microscopy.
|
|
Academic Article
|
Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice.
|
|
Academic Article
|
Sequences of immunoglobulin lambda 1 genes in a lambda 1 defective mouse strain.
|
|
Academic Article
|
Ultrastructure of rosette-forming cells in the mouse during the antibody response.
|
|
Academic Article
|
The bulk chromatin structure of a murine transgene does not vary with its transcriptional or DNA methylation status.
|
|
Academic Article
|
The transcription factor Spi-B is not required for somatic hypermutation.
|
|
Academic Article
|
The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
|
|
Academic Article
|
Targeting of AID to immunoglobulin genes.
|
|
Academic Article
|
Expression of immunoglobulin genes in transgenic mice and transfected cells.
|
|
Academic Article
|
High-frequency deletional rearrangement of immunoglobulin kappa gene segments introduced into a pre-B-cell line.
|
|
Academic Article
|
High expression of cloned immunoglobulin kappa gene in transgenic mice is restricted to B lymphocytes.
|
|
Academic Article
|
Mapping of immunoglobulin variable region genes: relationship to the 'deletion' model of immunoglobulin gene rearrangement.
|
|
Academic Article
|
Evidence for multiple immunoglobulin genes.
|
|
Academic Article
|
Turnover of myeloma messenger DNA.
|
|
Academic Article
|
Influence of metabolic inhibitors on the capacity of spleen cells to form hemolytic plaques and rosettes.
|
|
Academic Article
|
Delayed hypersensitivity in vitro.
|
|
Academic Article
|
Ssm1b expression and function in germ cells of adult mice and in early embryos.
|
|
Concept
|
MutL Protein Homolog 1
|
|
Concept
|
MEF2 Transcription Factors
|
|
Grant
|
AID in somatic mutation of immunoglobulin genes
|